Chie Emoto: search on Z-Library

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1

Prediction of drug intestinal absorption in human using the Ussing chamber system: A comparison of intestinal tissues from animals and humans

Miyake, Masateru, Koga, Toshihisa, Kondo, Satoshi, Yoda, Noriaki, Emoto, Chie, Mukai, Tadashi, Toguchi, Hajime

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 647 KB

english, 2017

2

Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings

Hayashi, Shigeo, Ohashi, Katsuyo, Nakata, Eriko, Emoto, Chie

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 3.56 MB

english, 2014

3

Methodologies for Investigating Drug Metabolism at the Early Drug Discovery Stage: Prediction of Hepatic Drug Clearance and P450 Contribution

Emoto, Chie, Murayama, Norie, Rostami-Hodjegan, Amin, Yamazaki, Hiroshi

Journal:

Current Drug Metabolism

Year:

2010

Language:

english

File:

PDF, 232 KB

english, 2010

4

Model-based precision dosing of sirolimus in pediatric patients with vascular anomalies

Mizuno, Tomoyuki, Emoto, Chie, Fukuda, Tsuyoshi, Hammill, Adrienne M., Adams, Denise M., Vinks, Alexander A.

Journal:

European Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 731 KB

english, 2017

5

Characterization of coarse particles in alumina powders by a wet sieving method

Kenji Nakahira, Tadashi Hotta, Makio Naito, Nobuhiro Shinohara, Yong-ick Cho, Shigemi Katori, Hideyuki Emoto, Tetsuo Yamada, Takashi Takahashi, Masataro Okumiya, Chie Kumagai, Keizo Uematsu

Journal:

Journal of the European Ceramic Society

Year:

2003

Language:

english

File:

PDF, 614 KB

english, 2003

6

Evidence of a Clinically Significant Drug‐Drug Interaction between Cannabidiol and Tacrolimus

Leino, Abbie D., Emoto, Chie, Fukuda, Tsuyoshi, Privitera, Michael, Vinks, Alexander A., Alloway, Rita R.

Journal:

American Journal of Transplantation

Year:

2019

Language:

english

File:

PDF, 442 KB

english, 2019

7

In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: a Comparison with SKF-525A

Emoto, Chie, Murase, Shigeo, Sawada, Yasufusa, Iwasaki, Kazuhide

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

8

Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients

Hoogdalem, Matthijs W., Emoto, Chie, Fukuda, Tsuyoshi, Mizuno, Tomoyuki, Mehta, Parinda A., Vinks, Alexander A.

Journal:

British Journal of Clinical Pharmacology

Year:

2019

Language:

english

File:

PDF, 1.47 MB

english, 2019

9

Effects of Histidine-Tag on Recombinant Human Cytochrome P450 3A5 Catalytic Activity in Reconstitution Systems

Emoto, Chie, Murayama, Norie, Wakiya, Sachiko, Yamazaki, Hiroshi

Journal:

Drug Metabolism Letters

Year:

2009

Language:

english

File:

PDF, 135 KB

english, 2009

10

Clinical applications of physiologically-based pharmacokinetic modeling

Emoto, Chie, McPhail, Brooks T., Fukuda, Tsuyoshi

Journal:

Therapeutic Drug Monitoring

Year:

2019

File:

PDF, 1.06 MB

2019

11

Discovery of 1-(β-amino substituted-β-alanyl)-N,N-dimethylindoline-2-carboxamides as novel nonpeptide antagonists of nociceptin/orphanin FQ receptor: Efficient design, synthesis, and structure–activity relationship studies

Hayashi, Shigeo, Ohashi, Katsuyo, Nakata, Eriko, Emoto, Chie

Journal:

European Journal of Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 3.24 MB

english, 2012

12

Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients

Hahn, David, Fukuda, Tsuyoshi, Euteneuer, Joshua C., Mizuno, Tomoyuki, Vinks, Alexander A., Sadhasivam, Senthilkumar, Emoto, Chie

Journal:

Journal of Clinical Pharmacology

Year:

2020

Language:

english

File:

PDF, 473 KB

english, 2020

13

Characterization of intestinal and hepatic P450 enzymes in cynomolgus monkeys with typical substrates and inhibitors for human P450 enzymes

Yoda, Noriaki, Emoto, Chie, Date, Shoichi, Kondo, Satoshi, Miyake, Masateru, Nakazato, Satoru, Umehara, Ken, Kashiyama, Eiji

Journal:

Year:

2012

Language:

english

File:

PDF, 769 KB

english, 2012

14

Age-Dependent Changes in Sirolimus Metabolite Formation in Patients With Neurofibromatosis Type 1

Emoto, Chie, Fukuda, Tsuyoshi, Mizuno, Tomoyuki, Cox, Shareen, Schniedewind, Björn, Christians, Uwe, Widemann, Brigitte C., Fisher, Michael J., Weiss, Brian, Perentesis, John, Vinks, Alexander A.

Journal:

Therapeutic Drug Monitoring

Year:

2015

Language:

english

File:

PDF, 128 KB

english, 2015

15

PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants

Emoto, Chie, Johnson, Trevor N., Neuhoff, Sibylle, Hahn, David, Vinks, Alexander A., Fukuda, Tsuyoshi

Journal:

CPT: Pharmacometrics & Systems Pharmacology

Year:

2018

Language:

english

File:

PDF, 2.99 MB

english, 2018

16

In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations Catalyzed by Human Cytochrome P450 Enzymes: A Comparison with SKF-525A and Ketoconazole

Emoto, Chie, Murase, Shigeo, Sawada, Yasufusa, Jones, Barry C., Iwasaki, Kazuhide

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2003

Language:

english

File:

PDF, 272 KB

english, 2003

17

Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure–activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives

Hayashi, Shigeo, Ohashi, Katsuyo, Mihara, Sachiko, Nakata, Eriko, Emoto, Chie, Ohta, Atsuko

Journal:

European Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.84 MB

english, 2016

18

Evaluation of intestinal metabolism and absorption using the Ussing chamber system equipped with intestinal tissue from rats and dogs

Miyake, Masateru, Kondo, Satoshi, Koga, Toshihisa, Yoda, Noriaki, Nakazato, Satoru, Emoto, Chie, Mukai, Tadashi, Toguchi, Hajime

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2017

Language:

english

File:

PDF, 531 KB

english, 2017

19

Utilizing Pediatric Physiologically Based Pharmacokinetic Models to Examine Factors That Contribute to Methadone Pharmacokinetic Variability in Neonatal Abstinence Syndrome Patients

McPhail, Brooks T., Emoto, Chie, Fukuda, Tsuyoshi, Butler, Dawn, Wiles, Jason R., Akinbi, Henry, Vinks, Alexander A.

Journal:

Journal of Clinical Pharmacology

Year:

2019

File:

PDF, 907 KB

2019

20

Causative agent of vascular pain among photodegradation products of dacarbazine

Mariko Asahi, Ryo Matsushita, Masami Kawahara, Tomoyuki Ishida, Chie Emoto, Nagao Suzuki, Osamu Kataoka, Chisato Mukai, Miyoji Hanaoka, Junko Ishizaki, Koichi Yokogawa, Ken'ichi Miyamoto

Journal:

Journal of Pharmacy and Pharmacology

Year:

2002

Language:

english

File:

PDF, 200 KB

english, 2002

21

Comparison of P450 Enzymes Between Cynomolgus Monkeys and Humans: P450 Identities, Protein Contents, Kinetic Parameters, and Potential for Inhibitory Profiles

Emoto, Chie, Yoda, Noriaki, Uno, Yasuhiro, Iwasaki, Kazuhide, Umehara, Ken, Kashiyama, Eiji, Yamazaki, Hiroshi

Journal:

Current Drug Metabolism

Year:

2013

Language:

english

File:

PDF, 564 KB

english, 2013

22

Web technology to support LHD experiment management

Nagayama, Yoshio, Emoto, Masahiko, Yoshida, Masanobu, Iwata, Chie

Journal:

Fusion Engineering and Design

Year:

2012

Language:

english

File:

PDF, 892 KB

english, 2012

23

Busulfan Pharmacokinetics and Precision Dosing: Are Patients with Fanconi Anemia Different?

Mehta, Parinda A., Emoto, Chie, Fukuda, Tsuyoshi, Seyboth, Brian, Teusink-Cross, Ashley, Davies, Stella M., Wilhelm, Jamie, Fuller, Kirsten, Vinks, Alexander A., Boulad, Farid

Journal:

Biology of Blood and Marrow Transplantation

Year:

2019

Language:

english

File:

PDF, 801 KB

english, 2019

24

Busulfan Pharmacokinetics and Precision Dosing: Are Patients with Fanconi Anemia Different?

Mehta, Parinda A., Emoto, Chie, Fukuda, Tsuyoshi, Seyboth, Brian, Teusink-Cross, Ashley, Davies, Stella M., Wilhelm, Jamie, Fuller, Kirsten, Vinks, Alexander A., Boulad, Farid

Journal:

Biology of Blood and Marrow Transplantation

Year:

2019

File:

PDF, 801 KB

2019

25

Species Difference between Cynomolgus Monkeys and Humans on Cytochromes P450 2D and 3A-Dependent Drug Oxidation Activities in Liver Microsomes

Emoto, Chie, Iwasaki, Kazuhide, Koizumi, Ryo, Utoh, Masahiro, Murayama, Norie, Uno, Yasuhiro, Yamazaki, Hiroshi

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2011

Language:

english

File:

PDF, 588 KB

english, 2011

26

P212 - PBPK modeling and simulation of morphine in virtual neonates generated using actual patient information

Emoto, Chie, Hahn, David, Euteneuer, Joshua, Mizuno, Tomoyuki, Vinks, Alexander, Fukuda, Tsuyoshi

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2020

File:

PDF, 59 KB

2020

27

S1.2 - Relevance of transporter and metabolic SNPS to pediatric treatment

Fukuda, Tsuyoshi, Emoto, Chie

Journal:

Drug Metabolism and Pharmacokinetics

Year:

2020

File:

PDF, 42 KB

2020

28

Erratum to: Efficient design, synthesis and structure–activity relationship studies of 1-(3′-substituted propyl)-4-arylpiperidines as non-peptide antagonists of nociceptin/orphanin FQ receptor: biological activities, metabolic stabilities and hERG channel bindings

Hayashi, Shigeo, Ohashi, Katsuyo, Nakata, Eriko, Emoto, Chie

Journal:

Medicinal Chemistry Research

Year:

2014

Language:

english

File:

PDF, 154 KB

english, 2014

29

Drug Metabolism and Toxicity in Chimeric Mice with Humanized Liver

Emoto, Chie, Iwasaki, Kazuhide, Murayama, Norie, Yamazaki, Hiroshi

Journal:

JOURNAL OF HEALTH SCIENCE

Year:

2011

Language:

english

File:

PDF, 183 KB

english, 2011

30

Arachidonic acid with taurine enhances pulmonary absorption of macromolecules without any serious histopathological damages

Miyake, Masateru, Minami, Takanori, Yamazaki, Hiroyuki, Emoto, Chie, Mukai, Tadashi, Toguchi, Hajime

Journal:

European Journal of Pharmaceutics and Biopharmaceutics

Year:

2017

Language:

english

File:

PDF, 1.02 MB

english, 2017

31

Blue light-emitting diodes induce autophagy in colon cancer cells by Opsin 3

Yoshimoto, Toshiaki, Morine, Yuji, Takasu, Chie, Feng, Rui, Ikemoto, Tetsuya, Yoshikawa, Kozo, Iwahashi, Syuichi, Saito, Yu, Kashihara, Hideya, Akutagawa, Masatake, Emoto, Takahiro, Kinouchi, Yosuke,

Journal:

Annals of Gastroenterological Surgery

Year:

2018

Language:

english

File:

PDF, 1.36 MB

english, 2018

32

Association of higher arterial ketone body ratio (acetoacetate/Î²-hydroxybutyrate) with relevant nutritional marker in hemodialysis patients

Inaba, Masaaki, Kumeda, Yasuro, Yamada, Shinsuke, Toi, Norikazu, Hamai, Chie, Noguchi, Koichi, Yasuda, Eikichi, Furumitsu, Yutaka, Emoto, Masanori, Ohno, Yoshiteru

Journal:

Year:

2020

File:

PDF, 1.34 MB

2020

33

Real-Time Data Streaming and Storing Structure for the LHD’s Fusion Plasma Experiments

Nakanishi, Hideya, Ohsuna, Masaki, Kojima, Mamoru, Imazu, Setsuo, Nonomura, Miki, Emoto, Masahiko, Yoshida, Masanobu, Iwata, Chie, Ida, Katsumi

Journal:

IEEE Transactions on Nuclear Science

Year:

2016

Language:

english

File:

PDF, 811 KB

english, 2016

34

The impact of CYP3A5 * 3 polymorphism on sirolimus pharmacokinetics: insights from predictions with a physiologically-based pharmacokinetic model

Emoto, Chie, Fukuda, Tsuyoshi, Venkatasubramanian, Raja, Vinks, Alexander A.

Journal:

British Journal of Clinical Pharmacology

Year:

2015

Language:

english

File:

PDF, 1.37 MB

english, 2015

35

Remote device control and monitor system for the LHD deuterium experiments

Nakanishi, Hideya, Ohsuna, Masaki, Ito, Tatsuki, Nonomura, Miki, Imazu, Setsuo, Emoto, Masahiko, Iwata, Chie, Yoshida, Masanobu, Yokota, Mitsuhiro, Maeno, Hiroya, Aoyagi, Miwa, Ogawa, Hideki, Nakamura

Journal:

Fusion Engineering and Design

Year:

2016

Language:

english

File:

PDF, 1.41 MB

english, 2016

36

Human pharmacokinetic profiling of the dipeptidyl peptidase-IV inhibitor teneligliptin using physiologically based pharmacokinetic modeling

Nakamaru, Yoshinobu, Emoto, Chie, Shimizu, Makiko, Yamazaki, Hiroshi

Journal:

Biopharmaceutics & Drug Disposition

Year:

2015

Language:

english

File:

PDF, 1.14 MB

english, 2015

37

Pretransplant Absolute Lymphocyte Counts Impact the Pharmacokinetics of Alemtuzumab

Marsh, Rebecca A., Fukuda, Tsuyoshi, Emoto, Chie, Neumeier, Lisa, Khandelwal, Pooja, Chandra, Sharat, Teusink-Cross, Ashley, Vinks, Alexander A., Mehta, Parinda A.

Journal:

Biology of Blood and Marrow Transplantation

Year:

2017

Language:

english

File:

PDF, 1.04 MB

english, 2017

38

Risk Assessment of Drug–Drug Interactions of Calcineurin Inhibitors Affecting Sirolimus Pharmacokinetics in Renal Transplant Patients

Emoto, Chie, Vinks, Alexander A., Fukuda, Tsuyoshi

Journal:

Therapeutic Drug Monitoring

Year:

2016

Language:

english

File:

PDF, 243 KB

english, 2016

39

Using a vancomycin PBPK model in special populations to elucidate case-based clinical PK observations

Emoto, Chie, Johnson, Trevor N., McPhail, Brooks T., Vinks, Alexander A., Fukuda, Tsuyoshi

Journal:

CPT: Pharmacometrics & Systems Pharmacology

Year:

2018

Language:

english

File:

PDF, 782 KB

english, 2018

40

Developmental pharmacokinetics of sirolimus: Implications for precision dosing in neonates and infants with complicated vascular anomalies

Mizuno, Tomoyuki, Fukuda, Tsuyoshi, Emoto, Chie, Mobberley-Schuman, Paula S., Hammill, Adrienne M., Adams, Denise M., Vinks, Alexander A.

Journal:

Pediatric Blood & Cancer

Year:

2017

Language:

english

File:

PDF, 678 KB

english, 2017

41

Alemtuzumab Precision Dosing in Allogeneic Hematopoietic Cell Transplantation

Arnold, Danielle E., Emoto, Chie, Fukuda, Tsuyoshi, Vinks, Alexander, Lane, Adam, Teusink-Cross, Ashley, Chandra, Sharat, Jordan, Michael B., Myers, Kasiani C., Nelson, Adam S., Davies, Stella M., Neu

Journal:

Biology of Blood and Marrow Transplantation

Year:

2020

File:

PDF, 183 KB

2020

42

Improved Glycemic Control with Teneligliptin in Patients with Type 2 Diabetes Mellitus on Hemodialysis: Evaluation by Continuous Glucose Monitoring

Wada, Noritsugu, Mori, Katsuhito, Nakagawa, Chie, Sawa, Jun, Kumeda, Yasuro, Shoji, Tetsuo, Emoto, Masanori, Inaba, Masaaki

Journal:

Journal of Diabetes and its Complications

Year:

2015

Language:

english

File:

PDF, 392 KB

english, 2015

43

Effects of Enzyme Sources on Midazolam 1-Hydroxylation Activity Catalyzed by Recombinant Cytochrome P450 3A4 in Combination with NADPH-Cytochrome P450 Reductase

Emoto, Chie, Murayama, Norie, Yamazaki, Hiroshi

Journal:

Drug Metabolism Letters

Year:

2008

Language:

english

File:

PDF, 139 KB

english, 2008

44

Comparison of Kinetic Parameters for Drug Oxidation Rates and Substrate Inhibition Potential Mediated by Cytochrome P450 3A4 and 3A5

Yamazaki, Hiroshi, Niwa, Toshiro, Murayama, Norie, Emoto, Chie

Journal:

Current Drug Metabolism

Year:

2008

Language:

english

File:

PDF, 200 KB

english, 2008

45

Discovery of small-molecule nonpeptide antagonists of nociceptin/orphanin FQ receptor: The studies of design, synthesis, and structure–activity relationships for (4-arylpiperidine substituted-methyl)-[bicyclic (hetero)cycloalkanobenzene] derivatives

Hayashi, Shigeo, Ohashi, Katsuyo, Mihara, Sachiko, Nakata, Eriko, Emoto, Chie, Ohta, Atsuko

Journal:

European Journal of Medicinal Chemistry

Year:

2016

File:

PDF, 1.84 MB

2016

46

Influence of OCT1 ontogeny and genetic variation on morphine disposition in critically ill neonates: lessons from PBPK modeling and clinical study

Hahn, David, Emoto, Chie, Euteneuer, Joshua C, Mizuno, Tomoyuki, Vinks, Alexander A., Fukuda, Tsuyoshi

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 942 KB

english, 2018

47

Population pharmacokinetic modelling of busulfan and the influence of body composition in paediatric Fanconi anaemia patients

Hoogdalem, Matthijs W., Emoto, Chie, Fukuda, Tsuyoshi, Mizuno, Tomoyuki, Mehta, Parinda A., Vinks, Alexander A.

Journal:

British Journal of Clinical Pharmacology

Year:

2019

File:

PDF, 1.47 MB

2019

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